Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications
Science & Math | Biological Sciences

Title:
Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications
Author:
-
ISBN:
0849330254
ISBN13:
978-0849330254
Size PDF:
1551 kb
Size epub:
1378 kb
Publisher:
CRC Press; 1 edition (November 29, 2004)
Language:
English
Other formats:
pdf, odf, mobi, cb7, azw, lit, ibooks
Rating:
3.8
Votes:
496
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Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications, and Therapeutic Implications brings together timely, authoritative reviews by renowned international leaders in the fields of ribozymes, RNA interference, DNAzymes and oligonucleotide decoys, with emphasis on biochemistry and translational research. The chapters on ribozymes include discussions of ribozyme subtypes, structure-function aspects, and therapeutic applications. This is followed by a comprehensive discussion of DNAzymes, their various subtypes, kinetics and biochemistry, and applications in target validation. Finally, the mechanisms and multiple therapeutic applications of double-stranded oligonucleotide decoys are described.
For readers ranging from graduate students to researchers seeking target validation for pharmaceuticals to clinicians seeking innovative cancer and cardiovascular therapies, no resource is more complete and up to date than Synthetic Nucleic Acids as Inhibitors of Gene Expression: Mechanisms, Applications and Therapeutic Implications.